VIP Peptide
$150.00
VIP Peptide
VIP (Vasoactive Intestinal Peptide) is a naturally occurring peptide hormone that plays a key role in various physiological processes, including vasodilation, immune response modulation, and digestion. Researchers are exploring its potential effects on cardiovascular health, inflammation regulation, and neurological function in research applications.
Potential Research Applications
VIP Peptide is being studied for its possible effects in several areas, including:
- Cardiovascular Studies: Investigated for its role in promoting vasodilation and supporting healthy blood flow.
- Immune Modulation: Studied for its potential to regulate immune responses and reduce inflammation.
- Neurological Function: Researched for its effects on neurotransmission and neuroprotection.
- Gastrointestinal Health: Explored for its possible role in promoting healthy digestion and gut motility.
- Anti-Inflammatory Research: Examined for its ability to modulate inflammation in various models.
✔ High-Purity Research Peptide – Produced with stringent quality control for scientific studies.
✔ Lab-Tested for Accuracy – Ensures reliability and consistency in research applications.
✔ Designed for Research Use Only – Not for human consumption or medical use.
The peptides are available for research and laboratory purposes only. Please review and ahere to our Terms and Conditions before ordering.
- Description
- Certificate of Analysis
Vasoactive Intestinal Peptide (VIP) Structure
Source: PubChem
What is VIP?
Vasoactive Intestinal Peptide (VIP) is a naturally occurring 28-amino acid neuropeptide that is critical in numerous physiological processes. Found primarily in the nervous system, gastrointestinal tract, and immune cells, VIP has been extensively studied for its regulatory effects on smooth muscle relaxation, immune modulation, neurotransmission, and cellular repair. Its therapeutic potential is being explored in inflammatory, neurological, and autoimmune conditions.
First identified in the intestines, VIP was initially recognized for its vasodilatory effects on the vascular system. Over time, research revealed its presence in other tissues and its involvement in various biological processes, including regulating circadian rhythms, inflammation, and glandular secretion.VIP is a peptide composed of 28 amino acids with a helical structure that facilitates binding to specific receptors. These receptors, VPAC1 and VPAC2, belong to the G-protein-coupled receptor (GPCR) family and mediate VIP's effects by activating intracellular signaling cascades, such as cyclic AMP (cAMP) pathways.
VIP binds to its receptors on target cells, triggering a cascade of intracellular events that regulate various cellular functions. Key mechanisms include:
- Relaxation of Smooth Muscle: VIP induces smooth muscle relaxation, particularly in the gastrointestinal tract, airways, and blood vessels.
- Immune Modulation: VIP suppresses pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α), while enhancing anti-inflammatory cytokines like IL-10.
- Neurotransmission: VIP acts as a neuromodulator, influencing synaptic plasticity and protecting neurons from oxidative damage.
- Cellular Protection: VIP enhances cellular repair mechanisms and protects tissues from apoptosis and oxidative stress.
VIP is recognized for its potent anti-inflammatory properties. It has been shown to modulate immune cell activity, suppress Th1 and Th17 inflammatory pathways, and enhance regulatory T-cell (Treg) function. These effects make VIP a promising molecule for research into autoimmune diseases and chronic inflammatory conditions.VIP has significant neuroprotective effects. It supports neuronal survival, reduces oxidative damage, and enhances synaptic transmission. Studies suggest VIP may play a role in mitigating neurodegenerative conditions, such as Alzheimer’s and Parkinson’s diseases, as well as improving outcomes in traumatic brain injuries.
VIP regulates intestinal motility, secretion, and absorption, making it a critical focus in gastrointestinal studies. It has been investigated for its potential to alleviate disorders such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and gastroparesis. As a vasodilator, VIP plays a key role in regulating vascular tone and blood pressure. It also supports respiratory function by reducing airway constriction and inflammation, making it a target for research in conditions such as pulmonary hypertension and asthma.
VIP is a central circadian clock regulator, particularly in the hypothalamus's suprachiasmatic nucleus (SCN). Research suggests that VIP helps synchronize biological rhythms, which has implications for studies on sleep disorders, jet lag, and shift work-related health issues. VIP’s ability to target multiple physiological systems makes it invaluable in studying health and disease. Its regulatory effects on inflammation, neuroprotection, and circadian rhythms position it as a key peptide for exploring therapies in autoimmune diseases, neurological disorders, and metabolic syndromes.
For Research Use Only
No Certificate of Analysis images available for this product.
