P21 – 10mg
$50.00
P21 Peptide – Research-Grade Peptide for Cell Cycle and Cancer Research
P21 Peptide, cyclin-dependent kinase inhibitor 1A (CDKN1A), is a crucial peptide in regulating cell cycle progression. It functions as a natural inhibitor that helps control cell growth and apoptosis. Researchers study P21 peptide for its potential impact on cell cycle arrest, cancer research, and cellular senescence.
Potential Research Applications
P21 peptide is being explored in various research areas, including:
- Cell Cycle Regulation: Investigated for its role in halting cell division, essential for tumor suppression and cell cycle control studies.
- Cancer Research: Studied for its potential to inhibit uncontrolled cell proliferation, making it a valuable tool in anti-cancer studies.
- Cellular Senescence: Explored for its effects on cell aging and programmed cell death.
- Molecular Biology: Utilized to understand the mechanisms of cell cycle regulation and p53 pathway interactions.
- Drug Development: Employed in investigating potential therapeutic interventions targeting cell cycle dysregulation.
✔ High-Quality Research Compound – Produced under strict quality control standards.
✔ Lab-Tested for Consistency – Independently verified to ensure accurate and reproducible results.
✔ Designed for Research Use Only – Not intended for human consumption or clinical treatment.
The peptides are available for research and laboratory purposes only. Please review and ahere to our Terms and Conditions before ordering.
- Description
- Certificate of Analysis
P21 is a protein encoded by the CDKN1A gene. It plays a crucial role in regulating the cell cycle, particularly controlling the progression from one phase to the next. As a cyclin-dependent kinase inhibitor, P21 inhibits the activity of cyclin-CDK2 or cyclin-CDK4 complexes.
These complexes are responsible for the transition from the G1 phase to the S phase of the cell cycle. This inhibition helps prevent uncontrolled cell division, making P21 vital for cell growth and tumor suppression.
P21 is often induced in response to DNA damage or stress signals, such as oxidative stress, UV radiation, and oncogene activation. It acts as a critical component of the p53 signaling pathway, a key regulator of the cell cycle and apoptosis.
When DNA damage occurs, p53 activates and upregulates P21. This leads to cell cycle arrest, giving the cell time to repair its DNA before continuing division. If the damage is severe, P21-mediated arrest can lead to apoptosis, or programmed cell death.
In addition to regulating the cell cycle, P21 influences other cellular processes like apoptosis, differentiation, and senescence. Researchers have studied its activity in aging, cancer, and degenerative diseases. P21 also plays a role in maintaining cellular homeostasis and preventing mutations that could lead to tumors.
In research, scientists use P21 as a marker for cellular responses to DNA damage or stress. They are also exploring P21 in cancer therapies, as regulating its expression can impact cancer cell growth and survival. However, P21’s role in different tissues and conditions remains complex, and more studies are needed to fully understand its potential in modulating activity.
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